在血液代用品研究方向,團隊近2年獲得四川省科技支撐計劃2項,四川省技術創新工程專項1項,四川省國際科技合作與交流研究計劃1項,累計立項經費192萬元;并與四川正康公司建立橫向聯合實驗室“新一代多功能代血漿的研究開發”,與中山新行健醫藥科技有限公司合作開展“血紅蛋白類載氧藥物質量標準研究”,累計立項經費160萬元。發表SCI論文5篇,中文核心期刊4篇。在輸血材料方面,建立了較為完善的生物材料的血液相容性評價平臺,獲得了國家自然科學青年基金及協和青年基金各1項,承擔全國醫療器械生物學評價標準化技術委員會和全國輸液器具標準化技術委員會標準起草和驗證工作2項,并與國內外多家企業聯合開展了包括醫療器械增塑劑溶出物研究,血小板保存功能研究,白細胞過濾研究等多項橫向項目,發表SCI論文2篇,中文核心期刊4篇,科研能力得到了國內外同行的認可。
近兩年來,經過全體成員的辛勤工作、共同努力,各方面都取得一定成果和積累,為團隊今后的發展打下了堅實的基礎。
In research direction of blood substitute, during the past two years, the team has obtained 2 Sichuan Science and Technology Support Programs, a Sichuan special technical innovation projects, a Sichuan Province international scientific and technological cooperation and exchange research program, and cumulative project funding was 1.92 million. In addition, the joint laboratory was established with Sichuan Zhengkang Corporation for “the study and development of new generation of multifunctional plasma substitute”, and the program “quality standard study of Hemoglobin oxygen-carrying drugs” was cooperated with Zhongshan Xinxingjian medical technology Ltd. and cumulative project funding was 1.6 million. The 5 SCI articles and 4 articles of Chinese core journals were published.
In research direction of transfusion materials, evaluation methods of blood compatibility of biomaterials were established. In 2014, a National Natural Science Foundation for the youth and a Chinese Academy of Medical Sciences and Peking Union Youth Fund was obtained, and two items of standard drafting and verification work were undertaken for Technical Committee of Standardization of Biological Evaluation on Medical Device and the National infusion equipments standard technology committee. Furthermore, we cooperated with Domestic and foreign enterprises for programs such as testing for plasticizer migration from kinds of medical devices, for the storage quality of platelet in platelet bags and quality of leukocyte filters etc. The 2 SCI articles and 4 articles of Chinese core journals were published, and the ability of research was recognized from Domestic and foreign counterparts.
Through hard work by all the team members in the past two years, each field has made some achievements and accumulation, which is a good foundation for the team to do better in the near future.
PI簡介:
劉嘉馨
研究員,中國醫學科學院北京協和醫學院碩士生導師,全國醫療器械生物學評價標準化技術委員會委員,中國生物材料學會理事,中國醫學科學院學術委員會委員,中國醫療保健國際交流促進會醫療保健器械行業專業委員會副主任委員,中國微循環學會血液流變委專業員會委員,四川省生物醫學工程學會常務理事,四川省輸血協會專家委員會委員,中國輸血雜志、國際輸血及血液學雜志編委。1985年畢業于上海復旦大學化學系,1988年畢業于成都科技大學高分子材料系獲碩士學位。近年承擔國家高技術研究發展計劃(863計劃)子課題、國家科技支撐計劃項目、四川省科技支撐計劃項目等各類科研項目20余項,獲得各類科研經費500余萬元,發表SCI論文、中文核心期刊論文40余篇。Prof. Jiaxin Liu
Committee member of Technical Committee of Standardization of Biological Evaluation on Medical Device, syndic of Chinese Society for Biomaterials, committee member of Academic Committee of Chinese Academy of Medical Sciences, Vice Chairman of China International Exchange and Promotive Association For Medical and Health Care, Committee member of Chinese Microcirculation Society of Hemorheology Professional Committee, Standing director of Sichuan Biomedical Engineering Society, Committee member of Sichuan Blood Transfusion Professional Committee, editorial board member of “Chinese Journal of Blood Transfusion” and “International Journal of Blood Transfusion and Hematology”.
Prof. Jiaxin Liu was graduated from Chemistry Department of Fudan University, and post-graduated from Polymer Materials Department of Chengdu University of Science and Technology. In recent years, J.X. Liu has been responsible for appropriate twenty important national projects, including branch project of National High-tech R&D Program (863 Program), National Key Technology Support Program and Sichuan Key Technology Support Program. Additionally, J.X. Liu leads his team to achieve about five million RMB technology research funding, and publish approximately forty SCI articles and Chinese Core Journals.
Transfusion biomedical engineering research team was established in April 2013, and it belonged to level A team of institute of blood transfusion. The primary research fields of this team includes critical technologies of blood substitute and the new generation of oxygen-carrying plasma; blood storage quality research such as the influence of nitric oxide on red blood cell deformability and the storage quality of high altitude blood; blood transfusion materials research such as evaluation of blood compatibility of biomaterials and research and development of transfusion equipments including Alliance bag type of leukocyte filters for whole blood, filters for platelet and platelet storage bags.
Tel:0086-28-61648520 E-mail: jxliu8122@vip.sina.com